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Their binding can be further reinforced by a protruding loop on the RBD

Component-resolved HPLC, dual-target LC-MS, and LAL endotoxin assays run in parallel, with results scored against pre-locked criteria

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From the gut compartment, the dose first enters the liver where some of it is metabolized and conjugated, and the rest enters the general circulation from where it is taken up by liver and tissues or excreted in the urine