These include the cost of the medication, potential side effects such as gastrointestinal disturbances and increased risk of thyroid tumors, the unestablished long-term safety in non-diabetic individuals, and limited availability due to high demand
A recent US survey of 60,000 people taking injectable GLP-1 medication found that one in seven were microdosing
In clinical electrophysiology departments, the combined workload produced by clinical and scientific work, in addition to administrative duties, writing of grant applications and academic obligations, create an unfavorable environment for focused application of basic findings into optimized patient care
Ferroptosis is defined by the accumulation of lipid peroxides and inactivation of glutathione peroxidase 4 (GPX4), and is typically initiated in the context of disrupted iron homeostasis, aberrant lipid metabolism, and mitochondrial dysfunction in the brain