retatrutide trials Eli Lilly infiltrates anti-obesity market as Phase III trial for begins Lilly's triple agonist delivers up

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We calculated a sample size of 120 patients needed (60 in each group) to be 80% certain that the upper limit of a 1-sided 95% CI will exclude a difference in favor of the standard group of more than 3% (the noninferiority limit) using Farrington-Manning score test

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effective contraception is recommended for women of childbearing potential Individuals with renal impairment : whilst no routine dose adjustment is required for the class, there is an increased risk of dehydration and acute kidney injury from gastrointestinal side effects, and monitoring is advised Individuals with hepatic impairment : limited data are available