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In this study, the abundance of immune cells was not strongly associated with the expression of TCA-related genes but was strongly positively correlated with the activity of the respiratory chain complex

Pills/troches = needle-free and convenient, but exposure can be lower or more variable person-to-person and product-to-product

Tirzepatide may be considered for its approved metabolic indications in these patients, but it should not replace or delay established autoimmune disease treatments

These observations should be interpreted with caution and warrant confirmation in further larger, adequately powered trials, specifically designed to address this question, ideally through targeted analyses of regulators of sulfur and NO pathways in pathological pregnancies with IPTB