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When GLP-1 receptors are activated at the scale that retatrutide achieves, the body interprets sustained caloric restriction as a famine state

A retrospective cohort study using real-world data from 1845 elderly patients with T2DM found that GLP-1 RAs use was associated with a significantly lower risk of developing OP, even after adjusting for multiple confounders including age, sex, BMI, smoking, and antihypertensive use

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