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Ozempic (Semaglutide GLP-1) Injections for Medical Weight Loss Q&A Semaglutide GLP-1, the active component in Ozempic, is effective for weight reduction

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While Alnylams Phase III APOLLO-B study hit both key primary and secondary endpoints, the FDA stated in the documents that the effects of patisiran compared to placebo on both endpoints were small, of questionable clinical meaningfulness, and may not be detectable by patients. Major discussion points during the adcomm meeting included whether these key endpoints were appropriate to ascertain clinical meaningfulness in the ATTR-CM population, and panelists expressed varying opinions on whether the magnitude of the benefit seen in trial data was clinically meaningful

If they determine its safe for you to stop the drug, theyll likely have you taper off it over time and provide other treatment recommendation to help you manage your type 2 diabetes