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Excess homocysteine has been shown to reduce both bone density and bone quality by damaging cells involved in bone turnover and interfering with the functionality of collagen
Endothelial and granulosa cells exposed to oxidative or perfusion stress activate NF-B and stabilize HIF-1, respectively, programs that drive inflammatory and survival gene expression (e.g., IL-6, VEGF, glycolytic reprogramming) and that have been associated with impaired follicular function in ovarian pathology [58, 59]
Some of the prototypical enzyme inducers cause an initial and transitory mitogenic response that increases the number of hepatocytes in the affected liver (Bentley et al
During I sc the voltage is clamped to values different from 0 mV enabling to estimate the TEER
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