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c , Proposed mechanism for tautomerization of (R)-2-hydroxymenthofuran by GST A1-1 44

Similarly, coronary artery disease patients with single, double, or triple-vessel stenosis and patients with acute coronary syndrome had a significant increase in malondialdehyde levels and the percentage of malondialdehyde release, associated with a marked decrease in GSH concentration, total antioxidant capacity and erythrocyte GSH peroxidase activity compared with controls (154)

The ratio of GSH to GSSG is a direct indicator of cellular redox status, and when that ratio shifts, it signals oxidative stress

Sies H, Stahl W, Sevanian A, Nutritional