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The immobility due to bed rest further enhances protein degradation pathways, as shown by spaceflight research and ground-based simulations 15

Yong, T

The peptide's activation of ERK1/2 and downstream transcription factors including Egr-1 drives expression of collagen synthesis genes while its enhancement of cellular migration ensures efficient fibroblast recruitment to sites requiring matrix deposition, creating optimal conditions for rapid yet organized tissue reconstruction

It is less invasive and more cost-effective for patients and clinics, especially those who do not provide infusions. You can view the full study here.