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These findings suggest that semaglutide and dapagliflozin effectively reduce inflammation in diabetic rats, with semaglutide showing a stronger anti-inflammatory effect

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Introduction The advent of incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their combinations, as pharmacological treatments for obesity and type 2 diabetes, has sparked intense debate about their role relative to traditional lifestyle interventions such as exercise and dietary modification

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