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Acest proces este extrem de important pentru meninerea nivelurilor stabile de zahr dup mas

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[9] [10] For patients with established cardiovascular disease, SGLT2 inhibitors are generally prioritised for cardiorenal protection, with GLP-1 receptor agonists with proven cardiovascular benefit considered when SGLT2 inhibitors are unsuitable

2.2.1 TGF- TGF- is the most potent pro-fibrotic mediator, inducing ECM, EMT, and pro-fibrotic mediators production by promoting the binding of Smad2/3 to Smad4, and driving myofibroblast differentiation to promote the PF process (Hu et al., 2018