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Therapeutic Potential of Emerging NAD+-Increasing Strategies for Cardiovascular Diseases

Based on the whole-body turnover rate of 1.33%/day for carnosine and the total amount of carnosine (45.5 g) in a 70-kg man (Spelnikov and Harris 2019), it can be estimated that the physiological need for this dipeptide by a 70-kg subject is 606 mg/day

Moreover, this enhanced the accessibility of the drugs