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Acts as a potent endogenous antioxidant, regulating pro- and anti-inflammatory pathways, and protecting against DNA damage and lipid peroxidation

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

L-glutathione, the primary skin-brightening active, shifts melanin production from eumelanin (brown-black pigmentation) toward pheomelanin (lighter pigmentation) by reducing the oxidative environment required for eumelanin synthesis and by inhibiting tyrosinase the rate-limiting enzyme in the melanogenesis pathway

This paper synthesizes results and experiences from the three main research activities of the project