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The core-H 1 H 2 H 3 probes could be rapidly adopted by the cells due to the targeted adsorption and endocytosis, which chiefly led to the higher level of nanospheres internalization into cells within 2 h 42,43

The adrenal glands produce hormones such as the stress hormone cortisol and adrenaline

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Despite this promise, several critical limitations remain: No large-scale, randomized controlled human trials to confirm efficacy, safety, or long-term impact Toxicology and pharmacokinetic data are lacking, especially for chronic use or high-dose regimens Only one stereoisomer (all-L form) has been tested