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Use sterile handling, avoid vigorous shaking and repeated freeze-thaw cycles, and do not use the material if the seal is damaged or if persistent particles, unexpected cloudiness, or discoloration is present after dissolution
For instance, mean duration of diabetes was much shorter in the CagriSema group (6.4 years) compared with semaglutide (9.2 years) and cagrilintide (10.7 years) [10]
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The buffer was prepared by mixing 19.6 g of sodium citrate tribasic dehydrate, 1 g of phenol and 16.5 mL of concentrated hydrochloric acid in water
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