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It causes the separation of DNA strands and by inserting itself between DNA base pairs, it disrupts DNA and RNA synthesis, thereby stalling the movement of topoisomerase II, leading to DNA damage and initiation of apoptosis (Johnson-Arbor et al., 2017)

Considering the public input received and further internal analyses conducted, we proposed to make the following modifications to the Overall Hospital Quality Star Rating methodology: (1) implement a 4-star cap for hospitals in the lowest-performing quartile of the Safety of Care measure group for the 2026 Overall Hospital Quality Star Rating, and (2) implement a blanket 1-star reduction for hospitals in the lowest-performing quartile of the Safety of Care measure group for the 2027 Overall Hospital Quality Star Rating and thereafter

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Right now, tirzepatide is often considered one of the best weight loss injections because many patients lose a large amount of weight while using it