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Certain types of people who should not be doing it include Type 1 diabetics as they may struggle with low blood sugar

10.1136/bmj.m4573 38 PiotrowskiK.BeckerM.ZugwurstJ.Biller-FriedmannI.SpoettlG.GreifM.et al (2013)

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Dihexa Pharmacokinetics and Clearance Mechanisms The dihexa half life is governed by hepatic metabolism and renal clearance