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Huibin Weng, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
This helps to replenish norepinephrine levels in sympathetic nerves with low neurotransmitter levels, better enabling them to mediate baroreceptor stimulated vascoconstriction that is necessary to maintain blood pressure and blood flow when the body position is shifted from a horizontal to a vertical position
Most clients are able to return to normal activities immediately following treatment
The percentages of participants who experienced AE leading to treatment discontinuation as well as of those who experienced gastrointestinal AE with oral semaglutide 50 mg (Tables 2 and 3) were similar to those observed with subcutaneous semaglutide 2.4 mg (in STEP-1 and STEP-2 trials 67% discontinued treatment due to AE, 3444% experienced nausea, 2132% diarrhoea and 2225% vomiting) [11, 29]
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