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Are there dosing guidelines, side effects, or injection site considerations

For example, if you always want to draw 50 units (0.50 mL) per dose for consistency: At 2.5 mg dose: Reconstitute for 5 mg/mL (2.5 divided by 5 = 0.50 mL) At 5 mg dose: Reconstitute for 10 mg/mL (5 divided by 10 = 0.50 mL) At 7.5 mg dose: Reconstitute for 15 mg/mL (7.5 divided by 15 = 0.50 mL) This "consistent draw" approach reduces the chance of dosing errors when transitioning between dose levels because you always draw the same volume

PMID 8591048

In other words, pills can take longer to raise B12 levels, so if you need a quick boost, injections are the better choice