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That meant compounders would be acting illegally if they compounded tirzepatide, the main ingredient in Zepbound and Mounjaro

Nat Genet

371 In a study examining the effects of GLP-1RA on osteoporosis induced by ovariectomy in aged rats, administering exendin-4 for 16 weeks prevented deterioration of the trabecular microarchitecture and increased bone strength

Published peer-reviewed research has established several mechanisms through which these medications support weight management: they help reduce appetite by acting on hunger signals in the brain, they slow gastric emptying which promotes a feeling of fullness after meals and they help regulate post-meal blood sugar responses