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a third of patients deteriorate to being house or bedbound (24, 2931), impacting activities of daily living, socialising, family life, emotional wellbeing, work, and education (23)

Clinical studies help clarify the connection: In simple terms: the trigger is the speed of weight loss, not tirzepatide itself

LA maintains the cellular antioxidant state indirectly through activating the NRF2 pathway, and the NRF2 pathway governs the expression of antioxidant genes (such as -glutamylcysteine synthetase (-GCL), NAD(P)H quinone oxidoreductase 1 (NQO-1), and superoxide dismutase (SOD)) for enhancing the cell's antioxidant capacity and anti-inflammatory response [34, 35]