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However, STEP 1 extension concluded that 1-year withdrawal of semaglutide results in regain of two-thirds of prior weight loss [97], highlighting that withdrawal of semaglutide results in weight regain which may be problematic in older adults who are already using polypharmacy approaches for comorbid disease

And It's bad

It too comes with a hefty price tag if you dont have insurance, though Ozempic (the brand name of the original semaglutide drug) is slightly cheaper than Mounjaro