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It activates melanocortin receptors MC1R and MC3R, suppressing NF-kappaB nuclear translocation and consequently reducing pro-inflammatory cytokine production including TNF-alpha, IL-6, and IL-1beta

doi: 10.1172/JCI57256 225 WangXWangLXuYYuQLiLGuoY

2011;12:e42637

Dont eat too quickly and dont have a large drink with meals, says Rubin, who works at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania