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6.4.1 Regulatory restrictions on EED use 6.4.1.1 Chemical-specific regulations European Union and United States regulations restricting BPA use in food packaging applications have achieved substantial exposure reductions, with mean population exposure levels declining by 63% in affected regions (140)

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[18] This should be initiated and monitored by specialists, with regular checks of PSA and haematocrit In cases where ED is refractory to medical management, specialist referral may be appropriateto urology for consideration of penile prosthesis implantation, or to endocrinology/andrology if hormonal causes are suspected

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