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During an active infection or a state of chronic immune activationsuch as that seen in Long COVID or ME/CFSthe immune system's consumption of L-Glutamine skyrockets

[14] Because the liver is the central organ of copper handling and a major site of oxidative stress during injury, a copper-carrying, antioxidant-supporting peptide has a plausible mechanistic story there but the data are old, experimental, and not human, and the founding observation that the same peptide stimulates growth in neoplastic liver cells is a reminder that acts on the liver is not synonymous with good for the liver in every context

(1981) published in European Neurology administered DSIP as a slow intravenous infusion at 25 nmol/kg to six healthy volunteers in a double-blind crossover design