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While there are no known direct pharmacokinetic interactions between semaglutide and common migraine medications, semaglutide's effect on gastric emptying may delay the absorption and onset of oral medications, including pain relievers and triptans

The AREDS (Age Related Eye Disease Study), was an extensive study that proved the benefits of oral antioxidants in the prevention of macular degeneration progression, and the AREDS formula of oral antioxidant vitamin supplements are recommended universally in the Ophthalmology community for the prevention of macular degeneration 4

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The study was reviewed and approved by the IRB of Samsung Medical Center (IRB approval number: 2021-06-064) and all methods were performed according to the IRB committees regulations