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When you might need a maintenance dose or another medication Before deciding what comes next, it helps to understand the tools available after tapering off tirzepatide

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Some individuals may feel mild discomfort or a pinching sensation during the injection process

Second, the final maintenance dose may be lower than what you would use with retatrutide alone, because the cagrilintide component provides additional appetite suppression and metabolic benefit that reduces the need for maximum retatrutide dosing