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J Endocrinol Invest (2013) 36:1520

Key Takeaways Tesamorelin targets belly fat specifically and reduces visceral fat by 20% in 26 weeks Ipamorelin offers gentler fat loss with fewer side effects and better long-term safety Both peptides boost natural growth hormone production but use different pathways Medical supervision is required for safe use of either peptide therapy What Are Growth Hormone-Releasing Peptides

Other biological variables, such as the age of the subject or the injection site, can influence how the peptide is absorbed and how effective it is

Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]