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Novo Nordisk may attempt to mitigate the impact from off-patent competition by protecting their share of Wegovy by enhancing weight-management services, or migrating patients from semaglutide to newer, patent-protected AOMs, including offering an oral version of semaglutide, effectively offering therapies with greater patient benefits

However, when combined with insulin or sulphonylureas, the risk increases, and dose adjustments of these concurrent medications may be necessary

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