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Description

HIF-1 metabolically controls collagen synthesis and modification in chondrocytes

In a renal proximal tubule-specific Tsc1 gene-knockout mouse model, downregulated AMPK phosphorylation was observed in the enlarged kidneys, which also exhibited aberrant proliferation of proximal tubule cells, renal interstitial inflammation, and fibrosis

Freeman and Co, New York, p179

doi: 10.3390/antiox11122336