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Two makers of GLP-1s, Eli Lilly and Novo Nordisk, established direct-to-consumer programs to allow patients to buy the medicines without using insurance at prices as low as $149 for starter doses and between $250 and $375 for monthly maintenance doses
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Many patients taking GLP-1 receptor agonists for diabetes or weight management report improvements in joint pain, prompting questions about whether these medications directly address musculoskeletal symptoms
Of note, in STEP 3 intensive behavioral treatment was also administered in both arms, and in STEP 4 all patients were initially assigned to semaglutide 2.4 mg but were randomized 2:1 to semaglutide 2.4 or placebo after 20 weeks 25
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