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Methylation impairment can result in an impaired ability to clear out certain toxins such as mercury and arsenic, and may lead to multiple chemical sensitivities, as our detox system can become overwhelmed

(1997) Structure, catalytic mechanism, and evolution of the glutathione transferases

Selenium for Male Fertility A trial reported that selenium with vitamin E improved semen parameters in a portion of participants, and some spontaneous pregnancies occurred

The detection principle is based on the cascade reaction of GR catalyzing the reduction of GSSG to GSH: GR first uses NADPH to reduce GSSG to GSH, and then the newly generated GSH reacts with the substrate DTNB to form yellow TNB and GSSG