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Alison Cave, MHRA's Chief Safety Officer, stated, "While the risk of serious side effects is very low, it is important that patients and healthcare professionals are aware of the symptoms and remain vigilant." She added, "We advise anyone using GLP-1 class drugs who experiences persistent abdominal pain, accompanied by nausea and vomiting, to consult a healthcare professional."

Some areas to monitor include: Changes in social engagement or communication Improvements in focus and learning Differences in sensory sensitivity Any new or worsening symptoms Regular check-ins with your healthcare provider can help assess whether LDN is making a positive difference

The phase one study is expected to begin in mid-2026 and will enroll about 20 overweight or obese adults who have not previously taken GLP-1 medicines

Hanta D, Akaaboune M, Lagord C, Murawsky M, Houenou LJ, Festoff BW, Vaught JL, Rieger F, Blondet B (1995 May) Beneficial effects of insulin-like growth factor-I on wobbler mouse motoneuron disease