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restricted to the outermost layers of skin , may be treated topically (Table 2) if the lesions location, the patients general health or the presence of co-morbidities mean excision is impractical or associated with an increased risk of complications or poor cosmetic outcome

Figure 1 It is well known that the pharmacodynamic property of metformin is anti-diabetic, but there is growing evidence that it has a number of extra-hypoglycemic effects

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GST Inhibitors and Their Therapeutic Importance GSTs emerged as viable therapeutic targets because specific GST isoenzymes have been shown to be over-expressed in numerous tumors