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If a fever does arise, consider hydrating, resting, and using herbal supports before turning to fever-reducing medications

Injectable GHK-Cu is not approved as a drug and may carry regulatory and safety concerns

doi: 10.3389/fcimb.2025.1673512 Received 26 July 2025 Revised 29 October 2025 Accepted 14 November 2025 Published 27 February 2026 Volume 15 - 2025 Edited by Soumyadev Sarkar, Arizona State University, United States Reviewed by Yoshihiko Tanaka, Fukuoka Dental College, Japan Chiara Scapoli, University of Ferrara, Italy Narjess Bostanghadiri, Tehran University of Medical Sciences, Iran Updates Copyright 2026 Gan, Chen, Zheng, Long, Cheng, Sulaiman and Huang

These antimicrobials and immunoglobulins can also be trapped in the mucus at the tethered mucin and secreted mucin layers, and this can be beneficial as it prevents the host defenses from being diffused away from the microbial targets