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When the body takes in insufficient fluid or loses excess amounts of fluid through sweating or illness, the urines concentration increases, and the yellow colour darkens

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MDMA-induced rhabdomyolysis (necrosis of myocytes from a rapid rise in cellular calcium), which can lead to myoglobin deposition in the kidney, along with extreme dehydration and electrolyte imbalances may also contribute to acute and chronic renal failure [1315, 86]