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After 72 h of dialysis, the resulting solution was freeze-dried by using low-temperature freeze dryers, yielding P3 (0.62 g), which was obtained as a white powder

The authors note that GHSs likely behave as functional somatostatin antagonists while enhancing GHRH-secreting neurons, that their GH-releasing effect is independent of gender but undergoes marked age-related variation, and that their activity is not fully specific for GH: they also produce slight prolactin release and, in Cushing disease, ACTH and cortisol responses

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