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The approval allows for earlier intervention and treatment with Rybelsus in adults with type 2 diabetes, when previously it was not approved as an initial (first-line) treatment option

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The temporal association between GLP-1 RA administration and lesion development, coupled with the absence of other known risk factors, suggests a possible drug-related etiology warranting further investigation

At minimum, this decision needs before-and-after numbers on IGF-1, fasting glucose, HbA1c, fasting insulin, plus lipids, blood pressure and fluid symptoms