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Figure 9 Studies have reported that alteration of genotypes also regulates the gut microbiota ( Nlrp3 KO reduces abundance of Bacteroides but enhances abundance of Desulfovibrio , [Ruminococcus] , Mucispirillum , Oscillospira , [Prevotella] , and Ruminococcus ( Fto KO mice consistently exhibit a high abundance of Lactobacillus, a low abundance of unclassified Porphyromonadaceae, and Helicobacter , which contributed to decrease depression- and anxiety-like behavior in mice ( Pgam5 KO male mice contained fewer Porphyromonadaceae-unclassified and higher Lactobacillus and A

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