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N Engl J Med 387(5):433443 Ashrafizadeh M, Yaribeygi H, Atkin SL, Sahebkar A (2019) Effects of newly introduced antidiabetic drugs on autophagy

Tirzepatide produced dramatic weight loss, roughly 20% of which was LBM, which is close to the quarter FFM formula

2019, Park et al

Patients who have combined semaglutide with consistent exercise, dietary improvements, and stress management sometimes maintain weight loss after stoppingthough this is the exception rather than the rule