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[2] [3] For many patients with established cardiovascular disease or high cardiovascular risk, SGLT2 inhibitors are preferred before GLP-1 receptor agonists where appropriate

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For patients I see in clinic, retatrutide may potentially be a highly impactful future tool to treat their obesity and transform their health trajectory." For the primary endpoint, participants taking retatrutide 9 mg and 12 mg lost an average of 64.4 lbs (25.9%) and 70.3 lbs (28.3%), respectively

At Peak Physical Therapy, weve identified several patient profiles requiring specialized approaches to muscle preservation during GLP-1 treatment: Adults over 50 : Age-related muscle loss (sarcopenia)accelerates after age 50, making older adults particularly vulnerable to functional decline during weight loss