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These features are essential for oxygen transport, since RBCs have to undergo repeated shape changes without fragmentation, to assure their passage and oxygen perfusion through all vascular networks, namely, through capillary blood vessels with smaller lumen diameter than that of RBCs [6, 7]

doi:10.1016/j.cell.2017.09.021 18

Effects of insoles and additional shock absorption foam on the cushioning properties of sport shoes