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Enhanced translation initiation and structural protein assembly contribute to muscle fiber repair

Variants in the FTO gene (rs9939609) influence appetite regulation and fat storage patternsindividuals carrying the risk allele preferentially store fat in the visceral compartment and often show larger visceral fat reductions on GLP-1 therapy

To overcome these obstacles, the establishment of harmonized international regulatory frameworks, validated analytical methodologies, and rigorously designed large-scale trials is essential

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