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The extracellular region contains one N-terminal SEMA domain, one PSI domain, and four IPT domains (IPT14)

Mechanistic studies to date suggest that GLP-1 signalling is more likely to modulate taste-related and eating-experience-related processing than to cause permanent sensory injury ( 5 Clinical and translational evidence: differential evidence across eating-experience-related endpoints during GLP-1RA treatment Across the current literature, GLP-1RA-associated eating-experience outcomes differ substantially in both definition and level of measurement

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