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This manifests as: Persistent fatigue and weakness Breathlessness, particularly on exertion Palpitations or rapid heartbeat Pale or jaundiced (yellowish) skin Glossitis (sore, red tongue) Neurological and psychiatric symptoms can be particularly concerning and may become irreversible if deficiency remains untreated for extended periods

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PYC has demonstrated substantial anticancer potential in various in vitro and in vivo models, supporting its role as a natural chemopreventive and therapeutic agent

C 8 is a less potent and efficacious PE than C 10 , (Brayden et al., 2014), suggesting that the efficacy of the TPE formulation may also depend on other components in the oily suspension (Brayden and Maher, 2021)