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Although the exact etiology of increased pathogen colonization is not known, it is generally believed that a reduction in good bacteria level may facilitate the entry and colonization of pathogens inside the vagina

Even when opening a vial, researchers should take steps to minimise exposure to open air, particularly in rooms where humidity is not strictly controlled

doi: 10.1056/NEJMoa1509225 251 HolmanRRBethelMAMentzRJThompsonVPLokhnyginaYBuseJBet al

A major clinical trial called the SELECT trial, published in the New England Journal of Medicine, followed over 17,000 people who were overweight or obese and had existing heart disease