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Two pathways are especially important in IGF-1 receptor research: PI3K/Akt/mTOR pathway MAPK/ERK pathway The PI3K/Akt/mTOR pathway is often discussed in relation to protein synthesis marker research, survival signalling, nutrient response markers and cellular growth models

9.1.1 Interprets and applies the appropriate evidence-based literature and standards for determining nutritional needs of target audiences

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Gastrointestinal side effects are the most frequently reported adverse events when first taking tirzepatide, occurring in approximately 1530% of patients during initial titration, with rates varying by dose and indication