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The fundamentals matter regardless of medication: Calorie deficit through proper nutrition High protein intake (0.7-1g per pound daily minimum) Resistance training 2-4x weekly Adequate sleep and stress management Sustainable lifestyle changes Medications like retatrutide can be powerful tools, but they work best when combined with the basics

This enhanced bioavailability translates to more consistent neurotransmitter support, particularly during periods of acute stress when catecholamine depletion occurs rapidly

PlexusDx compounded semaglutide is $189/mo month-to-month, or from $149/mo on the 6-month plan and can be adjusted based on your individual tolerance

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