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Chronic neuroinflammation has been reported to contribute to serotonergic, dopaminergic, and noradrenergic dysfunction in the brain (Song and Wang, 2011) and to lead to chronic immune dysregulation ( Figure 2 Previous studies found that pro-inflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin (IL)-6, IL-1, and C-reactive protein (CRP), are markedly increased in the blood and CSF of patients with depression (Hestad et al., 2016

If you are breastfeeding, consider pumping a bottle so someone else can handle one nighttime feeding, giving you a longer uninterrupted stretch

Duration: Typically resolves within 2-4 weeks without intervention

Biol Psychiatry 75:798806 King AC, Hasin D, OConnor SJ et al (2016) A prospective 5-year re-examination of alcohol response in heavy drinkers progressing in alcohol use disorder