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When focused on VAT-restricted mice ECs, single nucleus RNA transcriptomic has recently displayed their lower expansion coupled with a differential gene expression that modify with obesity severity

NCT06015893 Semaglutide Therapy for Alcohol Reduction (STAR) Status: Recruiting This study will test the safety/tolerability and early efficacy of subcutaneous (s.c.) semaglutide at the dose of 2.4 mg/week or maximum tolerated dose (MTD) as a potential new treatment for alcohol use disorder (AUD)

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As women with PCOS present also an imbalance between male and female hormones as their ovaries tend to produce androgens in excessive quantities, such phenomena of hyperandrogenism and/or insulin resistance in non-obese women with PCOS may be associated with the lowering of serum levels of LC [75]